A scientist tries to solve world hunger only to see things go awry as food falls from the sky in abundance. Bill Hader will voice Flint Lockwood, a young inventor who dreams of creating something that will improve everyone's life. Anna Faris, who recently turned heads as the star of the comedy hit The House Bunny, takes on the role of Sam Sparks, a weathergirl covering the phenomenon who hides her intelligence behind a perky exterior. James Caan plays Tim Lockwood, Flint's technophobic father. Andy Samberg plays Brent, the town bully who has plagued Flint since childhood. Bruce Campbell plays Mayor Shelbourne, who figures out that Flint's invention can put the town, and more importantly himself, on the map. Mr. T plays the by-the-rules town cop Earl Devereaux, and Tracy Morgan takes on the role of Earl's rule-breaking son, Cal.
- Based on the bestselling children's book written by Judi Barrett and illustrated by Ron Barrett